This guide contains information about places where you can stop for the night when driving from
Saint Louis, Missouri to Chicago, Illinois.
Total distance for the trip is around 297 miles with a driving time of approximately 4 hours 24 mins.
Cities and towns with hotels that are on the fastest route between Saint Louis and Chicago
are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)
96.7 miles from Saint Louis (1 hour 31 mins)
202 miles from Chicago (3 hours 6 mins)
168 miles from Saint Louis (2 hours 31 mins)
133 miles from Chicago (2 hours 4 mins)
